It's either a bad driver or a piece of hardware causing your problem, usually USB-related in my experience.
Try booting in Safe Mode (no third party drivers or programs automatically start). If you still get the freezing, it's probably hardware. If no freezing occurs, it was a driver or program.
If it's hardware, my money is on a USB device or a hard drive. Try unplugging all USB devices other than the mouse to see if the issue still occurs.