I'm no expert on Ryzen, but plan to get one in a few months time after some patches, bios updates etc come through to improve it's stability.
That vcore voltage is too high for 24x7. It's not like their older CPUs. Should be no higher than 1.35 to 1.40 if you want CPU to last.
Memory compatibility is an issue right now. Drop the ram to 2133MHZ to begin with to remove that potential issue, while you work on the CPU overclock.
Check for any other bios updates available...