Are you sure all the TV/monitor settings are correct? As in resolution, 60Hz and no overscanning.
The one thing I can think of that could cause something like not being able to re arrange columns ect. is that something is messing with the softwares click detection. Something like it using absolute location and then getting confused by scaling or something.
If seen thous types of things happen in a few games when not running native resolution.
Or alternatively some other...