Pros: Overclocking features, Asus Fusion Northbridge Cooler
Cons: No USB3, SATA 6Gb/s Support.
All of the features of full sized boards of similar vintage are available. There is support for six core processors, SLI, Crossfire, triple channel memory, ICH10R RAID, and a X-Fi branded integrated audio processor (not Creative silicon, but software).
The clear advantages the board offers over the Rampage III Gene are eSata support, the LCD poster and a Asus Fusion design- modular NB/Power phase cooling setup. The later allows the tiny NB heatsink to be removed, and replaced with either a proper HSF, or waterblock. The power regulation and the NB will remain connected via the heatpipe and will both be cooled by the replacement heatsink/block. With the popularity of tower style HSF and LCLC kits, the lack of cooling air flow across the NB heatsink in normal situations will cause the temperatures to skyrocket when attempting very high Bclk speeds. This feature was available on select Asus ATX boards, of the era, but has sadly fallen out of favor.
If you're looking for a phenomenal micro ATX 1366 board, and don't mind the missing USB3, and Sata 6Gb/s support, you owe it to yourself to source a Asus Rampage II Gene.
-Ronin de Beatrice