Pros: Durable, stable, mil spec, 5yr warranty. PCIe 2.0 x16/x16 mode, USB 3.0, SATA III
Cons: Difficult to color coordinate with other components (if that's important to you)
I have ran this mobo stock now for 15 months without a single issue. Very heavy use (12-15 hrs per day) (gaming, protein folding, image processing, writing).
Easy to install and set up. Comes with a detailed manual that answered all my 'first build' questions. Easy and flawless bios configuration and windows 7 setup. Despite the very unique green and tan color, it looks great in the case. I rather like the color actually and seek to find components to match (RAM, etc,)
Board layout is rather standard and works well for me with a single GPU. Plenty of room for RAM cooling fans and a liquid CPU Cooler. Crossfire/SLI ready, and with dual PCIe 2.0 at x16/x16 mode. However, due to the layout of the two PCIe 2.0 slots, Crossfire/SLI may be an issue without a custom GPU cooling solution. (top card will sit directly on top of the lower card, which may cause a cooling issue with the top card.)
Board runs cooler than most boards it seems. CERAM!X Tech seems to be working nicely. I have read that the northbridge does run warm, but usually stays around 47 to 52 degrees Celsius for me on my normal workload which isn't bad at all.
Brutally inexpensive compared to other comparable boards. $200 is very little to pay for a board of this quality. And ASUS stands behind this product with a 5 yr warranty.
ASUS is a very reliable company with very reliable products. I cannot comment on the quality of ASUS technical support since after over a year of very heavy use, I have not needed technical support at all when it comes to this motherboard.
Overall, I would (and have already), recommend this MOBO to other enthusiasts and will certainly go with another ASUS Sabertooth TUF line of MOBOs for my next computer motherboard.