Pros: Inexpensive, 1920x1080 output, supports multiple monitors, runs Source-engined games and GTA4 with no problems.
Cons: Low PPD output, lags heavily when trying to do anything while folding on it.
I've run my 2236vw and an HP vs17e off this card at the same time, the AOC via DVI or HDMI and the HP via VGA. I currently run just a single monitor setup, due to limited desk space.
The GT 220 isn't a perfect card, though - it's only good for about 2.5k PPD, and it'll cause lagging in the system when you try to do anything while it's folding. However, it does run very cool while folding, with the fan never getting over 40-50%. The EVGA Precision software allows limited overclocking of this card - up to the levels of the factory SuperClocked version. Any higher than that, and the drivers crash.
In closing, with all aspects taken into consideration, it's a pretty darn good card. Is it worth buying when you can get a Fermi card now for about the same price? That's up to you to decide.