Ok here's my two cents, being a graphic designer and a videographer. I can give you a run down of the basics but if you want an actual specific list, let me know and I can build one for you but there are the basics... aside from your intel platform you'll need a large pool of RAM - anything from 12 gigs to 16 gigs is more than enough, 8 gigs is great, too but because of your large budget lets go for 12-16 especially for the video rendering. Second, if you're using Adobe's creative suite for anything design related (which is industry standard) you'll have to go with an nVidia graphics card solution for the moment since Adobe only really supports the CUDA function right now when it comes to video rendering. Those CUDA cores will knock some serious time off the rendering queue as opposed to having to use the CPU to render. So in this case, I'd recommend SLI-ing two GTX580s or two GTX590s if you had the cash to spare. Next up, because of the nature of the mercury engine and the Creative Suite as a whole, they use something called "Scratch Disks" I do not recommend using SSD's as your scratch disks as they only have so many read and writes before they fail, what I'd do and actually do, do, is buy a few raptor drives and use them as your scratch disks exclusively and run your operating system and creative suite off the SSD disk for faster functionality.
Hope that helps.
Edit: Adding: I almost forgot, you need screens! This is a HUGE thing. You need a screen that represents the most accurate printing colors and palette you're using.
Those screens will reproduce Adobe's RGB palette to the 98th percentile utilizing over a billion colors. It's definitely a must.Edited by LocKDowN2222* - 4/26/11 at 9:17pm