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[SMH]Aussie researchers closer to HIV vaccine

post #1 of 32
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Quote:
Australian researchers are one step closer to finding a vaccine for HIV, and hope to be able to offer a preventative jab within the decade.
Experts at The University of Melbourne have found that people with HIV produce antibodies called ADCC, which trigger the immune system to find and attack the virus.
Source.
    
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post #2 of 32
Great, 1 step closer to no more use of protection
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post #3 of 32
What about all those other STDs you can catch...
    
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post #4 of 32
I don't think it will work. HIV is one of the fastest mutating viruses known. The enzyme "reverse transcriptase", the enzyme that replicates the viral genome, is inherently inaccurate. It introduces many mutations. This rapidly accelerates the evolution of the virus.

Antibodies recognize a certain "epitope" (yes my user name ). This epitope is usually a specific sequence of amino acids. If you alter the genetic code you alter the amino acids. If you alter the amino acids you alter the epitope and the antibodies don't work anymore. Most infectious micro organisms are experts at shifting their epitopes like this.

I wish them all the luck in the world, but I'm not holding my breath...
    
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post #5 of 32
Wow good read
    
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post #6 of 32
Quote:
Originally Posted by Atomfix View Post
Great, 1 step closer to no more use of protection
If you see the actual numbers of people with Human Papilloma Virus, Chlamydia, Gonorrhea, Herpes, Hepatitis etc. you would put in a rubber suit before walking into a crowded bar...

It's downright scary how many people have STDs.
    
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post #7 of 32
One step closer to booming population.....
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post #8 of 32
I thought HIV was God's way of smiting fornicators worldwide...this won't due...
post #9 of 32
Quote:
Originally Posted by hollowtek View Post
I thought HIV was God's way of smiting fornicators worldwide...this won't due...
This.

Even if this vaccine is released widely, I still believe people who got infected HIV voluntarily should be refused a vaccine because they chose not to wear protection and took risk. You take risk, your fault if it goes wrong.
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post #10 of 32
Quote:
Originally Posted by Console-hater View Post
This.

Even if this vaccine is released widely, I still believe people who got infected HIV voluntarily should be refused a vaccine because they chose not to wear protection and took risk. You take risk, your fault if it goes wrong.
The vaccine can't cure HIV, only prevent it. HIV infects T-cells, the very cells that kill virus infected cells. You can't destroy HIV when it is destroying the cells that would destroy it first... That's what makes HIV so tricky. It's like it specifically targets the exact defenses your body has against it.

If you are able to acquire the antibodies before you ever are exposed to the virus then there is the possibility that the antibodies will bind the virus and let your immune system target it before it ever actually infects you. That's the entire idea behind a vaccine.
Edited by Epitope - 5/6/11 at 9:18am
    
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