Originally Posted by Aniket
Just saw a review that msi is launching
msi gtx580 lightning extreme edition 3gb,
so again msi is gowing to have the crown & that 3gb card will be better than all the gtx580's mentioned in the poll,
now I have started considering msi to be the best non-reference gpu maker,
well done msi!!
Any of these cards with aftermarket coolers will do very well in a single card configuration.
However, if watercooling and/or multi-GPU setups are going to be in order, where multiple cards are going to be sandwiched together, then reference cards will be the better choices as they won't be starved for air, and they will have the broadest offerings for waterblocks.
"Best" is really a subjective matter.