Originally Posted by Narzon
Audio Creation, 44.1KHz sample rate, bit-matched playback.
Just to clarify, this is to achieve the most accurate reproduction of what you're meant to hear. "Best" is subjective, nothing stops you from playing with the EQ if you want. I believe there's a feature called Crystallization or something to that degree that supposedly cleans up lower quality MP3s. SVM normalizes the volume, making quiet sounds in music louder, and louder sounds quieter. Experiment if you want, but the above method is the accepted for accuracy.
Exactly what I was going to say. Audio creation mode with 24 bit 44.1 & bit-matched playback is the most accurate and sounds the best through my DT 990s. However, with other cans (e.g. ATH-A700s) I added a little bass and scooped the trebles a bit with the equalizer in entertainment mode.