I am not sure what you have already so it is difficult.
The best CPU IMO is the 2600K
The 2500K would do the job, but you say you want the best ....
I think a Asus WS P67 would be prudent as it has 16 2x lanes that provide seperation for the GPU's
570 SLI or 6970 CF would be a good solution as not to really suck up the budget on cards being you are looking for everything
Next with this budget I would shoot for some fast memory with the best timings
Just remeber, everything you are paying for is for the end result of fantastic graffics ..... that being said a top end S-IPS panel, I would try to sneak in a 27" size and then put the rest of thie system together useing the rest of the budget making sacrafices where you must, But Again, don't skim on the pictiure, too many make the mistake of spending 2K and cheap out on a poor sceen
I am one of them and I have learned my lesson as I save for a new 30" IPS
great Core components
skimp on hard drives, keys case, cooler and a mouse if you must, they are easy to upgrade over time anyway
Preformance and screen are what is most important, the rest is window dressing
if you find your self with a bit extra go SSD for the OS even last gen is very fast if you can find a deal on one
good luckEdited by Witchdoctor - 8/4/11 at 4:09am