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[CBS] North Texas researchers create ultimate flu shot - Page 3

post #21 of 74
Haven't gotten the flu shot in years..haven't needed it....yay for superior genes....except sinus infections..DOH
post #22 of 74
Quote:
Originally Posted by ALiShaikh View Post
Please link to these documented incidents. Vaccines have saved billions of lives by eradicating Small pox, Polio, and others. I'd rather not play my luck and pray I don't get Polio, when it is easily preventable.
I said I think vaccines are good. Bear with me means attempt to be objective. The CIA launched a fake vaccination trial in Pakistan before Bin Laden was killed, all over the news. Google it.

Also, seasonal Influenza does not equal Polio.

Quote:
Originally Posted by ALiShaikh View Post
What I can't believe is that there even OCNers who are against vaccines.Especially a mod. Do you really buy into the "Vaccines are population control" when it has proven time and time again that it is the exact opposite? You are the type of people who wont get your kids vaccinated and then as soon as they visit another country they would get horribly sick and possibly die.
Read thoroughly before attempting to bash, please. I'm not against vaccines.

Quote:
Originally Posted by trueg50 View Post
While people do have immune systems that deal with most threats, your immune system cannot deal with what it has never encountered yet. It has to encounter the strain of flu in order to built resistance/immunity to that strain (thus how the vaccine works).

This year there are many strains of the flu going around, this years vaccine is target at what is believed to be the most common. This vaccine would save all the guess work.
I know how vaccines (generally) work, I'm just curious if you were saying that this new compound in the article works by elevating a natural immune response or if it is something novel.
Edited by _02 - 11/7/11 at 8:11am
    
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post #23 of 74
This is interesting - very interesting indeed.
They seem to be taking an entirely new approach on how to fight the flu.

My question is, can it work against other infectious diseases as well? If this REDD-1 protein can defend against the flu, is it effective against anything else?

Also, how does the protein work?
Quote:
The scientists discovered that when there is less REDD-1 protein in a cell, viruses like the flu can invade and corrupt the cell in a matter of hours. But when this compound is added, boosting the presence of the REDD-1 protein, the flu (no matter what strain) is held at bay.
While I'm happy for their "discovery," I'm eager to know exactly how the protein works to prevent infection.

And are there any negative side effects related to increasing the protein's concentration?

It seems like a neat concept, but it's all still very vague <.<; or at least that's how I feel about the information in the article.
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post #24 of 74
Quote:
Originally Posted by KusH View Post
We have immune systems for a reason. Let them do their jobs. I don't know why people seem to think they are doing something beneficial for themselves by pumping themselves full of vaccines.
Yeah, we have immune systems, and those immune systems constantly improve by killing those of us who have weaker ones. Part of the beauty of being human is being able to counter natural selection and allow the "weaker" of us to continue living. Vaccines have already saved millions of lives, and while they certainly do need extensive testing, a new one is almost always going to be extremely beneficial. Great news.

EDIT: The flu for most of us is little more than a prolonged cold, but for the elderly, the young, and those in other countries, it can definitely be a fatal disease. Don't underestimate the importance of this thing.
post #25 of 74
More money for big pharma.
post #26 of 74
Thread Starter 
Quote:
Originally Posted by Narzon View Post
Yeah, we have immune systems, and those immune systems constantly improve by killing those of us who have weaker ones. Part of the beauty of being human is being able to counter natural selection and allow the "weaker" of us to continue living. Vaccines have already saved millions of lives, and while they certainly do need extensive testing, a new one is almost always going to be extremely beneficial. Great news.

EDIT: The flu for most of us is little more than a prolonged cold, but for the elderly, the young, and those in other countries, it can definitely be a fatal disease. Don't underestimate the importance of this thing.
Exactly.

For thousands of people every year, they don't just get a little sick and play COD for a few days; their bodies are too weak to survive the infection.

Hospitals and nursing homes have manditory vaccinations for their nurses/doctors to keep them from getting sick, and passing the infection on to the weaker patients. Same thing why if you are sick and are planning on visiting a nursing home, you should either not go, or wear a face mask.

Quote:
I know how vaccines (generally) work, I'm just curious if you were saying that this new compound in the article works by elevating a natural immune response or if it is something novel.
I have no greater insight into this, but I believe it sounds like instead of the virus entering the body and hijacking cells to use to reproduce.

In computer terms, the hacker (virus) tries to hack a weak system on a network, gain a foot hold, and use that foot hold to hack other systems on the internal network (the body). If you add a firewall to all computers, the hacker is denied access to all computers, including the foothold computer the hacker would normally exploit. The hacker cannot hack the weaker foothold server and thus cannot gain entry to any other systems on the network from that server.
    
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post #27 of 74
Quote:
Originally Posted by 06tb06 View Post
More money for big pharma.
Not really. I think they'd profit more from constant annual vaccinations and/or sales of medicines to alleviate the flu than they would from one life-time vaccination. Pharmacies tend to avoid breakthroughs like this if anything.
post #28 of 74
Quote:
Originally Posted by trueg50 View Post
For thousands of people every year, they don't just get a little sick and play COD for a few days; their bodies are too weak to survive the infection.
Definitely, immuno-compromised people should avail themselves of vaccines.

I'm going to run this by my "super genius scientist friends" to see if they know. I'm just interested if REDD-1 is part of the normal immune response. If so, the drug would boost REDD-1 globally without gambling on getting the strain right in a vaccine.

OR

If REDD-1 just so happens to prevent infection, so they boost it artificially. That would worry me more, because the body is not naturally designed to have elevated REDD-1 as part of the immune response.

Quote:
Originally Posted by Narzon View Post
Not really. I think they'd profit more from constant annual vaccinations and/or sales of medicines to alleviate the flu than they would from one life-time vaccination. Pharmacies tend to avoid breakthroughs like this if anything.
FWIW - they don't say it is a vaccine, it is a compound. I would imagine you would need to have it administered once or multiple times during the flu season to elevate levels of the protein REDD-1. A vaccine would be dependent (as I understand it) on a specific strain, which would defeat the purpose of it being globally effective.

/speculation
Edited by _02 - 11/7/11 at 8:23am
    
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post #29 of 74
Quote:
Originally Posted by 06tb06 View Post
More money for big pharma.
How true. Instead of funding things that make our lives better by keeping us from getting sick, allowing us to live longer, and all of the things the have given us the ability to sit around on our arses day in and day out overclocking our little computers, we should still be using roots and berries to drive away the evil spirits that get inside of us.

[/sarcasm], for you paint eaters out there.

Back on topic, REDD1 seems to have an interesting history, if you care to google the back story. And anything that will cut down on incidents of illness is cool beans in my book. There are few common events that are worse than becoming ill, especially when your illness is ill timed.
post #30 of 74
Quote:
Originally Posted by _02 View Post

I don't think that it would elevate REDD-1 levels permanently. You'd probably need to get the shot every year, potentially more than once a year during flu season. But there isn't any info in the article so that is speculation.
Then I misunderstood. If that's the case, it's less of a breakthrough than I had thought, though it certainly makes life easier for the researchers who need to create a new vaccine every year.
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