Load line calibration is best explained in this thread (second post): http://www.overclock.net/t/1313466/cpu-load-line-calibration-what-is-it . My understanding is it up's the vcore voltage dynamically to compinsate for vdrop (drop in vcore voltage when underload) if you are getting bsod on prime95 this could be due to vdrop llc could possibly make the clock speed stable. Does increase heat so id recommend medium-high settings rather than max.
With llc set to extreme on my machine i got 3.8ghz stable @ 1.32v if i set llc down one setting to high it will bsod 5 minutes in prime95.
Also if your mobo give you the option, try unlocking the cores manually and disable the defective core.
Edited by JoinTheRealms - 2/18/13 at 4:40pm