You just need an all in one cooler and compatible(Sigma_Cool/GPU Cool/ect) bracket or the time to mod the stock bracket to fit.
For most users the Asetek(most round coolers, but not the CoolerMaster or newer Antec units. they work as well with the GPU Cool from richie_2010
) based coolers are more easy because they do not have to be rotated 45 degrees(on some cards), but the 45 degree rotation does NOT hurt performance in any way.
Now you also have to try to get some air flowing over the VRMs(Voltage Regulation Module. The Mosfets are the things that get hot) if they already have a heat sink on them, great. If not some users prefer to install heatsinks on them(take care to not short them out.). A fan blowing on the vrm section of the board is a very common way to lower the temperatures of the vrms and keep them from overheating.
If your core is recessed, you will also need a copper shim to take up the extra space as that thick of thermal paste would kill performance.Edited by Nukemaster - 3/15/14 at 7:13pm