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[ctv]Canadian-made HIV vaccine approved for human testing - Page 3

post #21 of 94
Quote:
Originally Posted by Lazloisdavrock View Post

Canada <3

yeahhh you gotta love us fellow canadian smile.gif
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post #22 of 94
Quote:
Originally Posted by matty0610 View Post

I think the problem is, is why does there need to be a placebo pill? We already know for a fact nothing else discovered so far can remotely count as a vaccine. So why have a group of people who truly believe that they are getting real help when all they are is getting a sugar pill? The thing with HIV is that once it turns into full blown aids they are in trouble. Since HIV and AIDS are two different beasts which one can assume that the Vaccine doesn't help those with full on AIDS.
Yea there is the "glory" of helping to get a cure, but is it really glory when you're the one dying but you honestly believe that you might be better? HIV can turn into AIDS VERY easily in 3 years.


really?

but then again you're the op who posted that article in the first place with a stupid comment at the bottom
Quote:
Originally Posted by matty0610 View Post

I was always taught HIV turns into AIDS. Cause HIV is an STD not AIDS.
EDIT:
HIV cause AIDS according to Wiki

you didnt know this?
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post #23 of 94
Canada +1 thumb.gif
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post #24 of 94
Too bad the Biochemists in United States, specifically DARPA, already created the cure.........too be fair, they were the ones who made AIDS in the first place though.
Just FYI, sick people is what makes money.
Do you want to know how much money is made from sick people in this country?

Why cure people when you can make money of them?
Socialism at its finest.

lolwut.png

do you have the slightest idea what does socialism mean? you're talking nonsense.
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post #25 of 94
Quote:
Do you want to know how much money is made from sick people in this country?
Why cure people when you can make money of them?
Socialism at its finest.

lolwut.png
do you have the slightest idea what does socialism mean? you're talking nonsense.
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post #26 of 94
Quote:
Originally Posted by Mkilbride View Post

2.7 million a year. Damn people...

its less than .034% of the population or a ratio of .0003375


Cancer, Malaria, and TB are much more serious.
 
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post #27 of 94
Quote:
Originally Posted by Squirrel View Post

Eh, seriously? You think that they won't tell the volunteers that there is the possibility they may end up with a placebo and not the real vaccine but instead tell everyone they are all getting the real deal and if it turns out that they didn't, they just put on their trollface and say "oops forgot to mention it!"?
I don't know what the regulations are in the U.S., but in Canada they pound it into your head in every research methods class that not disclosing the potential risks to participants is not only unethical but also illegal.

In the US, you're legally obligated to do exactly as you said.

Every participant in the study is told that they're taking part in a double-blind (pretty much all human trials are) experiment, and that there is a chance they will not get the drug itself but a placebo. The participants then sign a waiver declaring that this very statement was explained to them, among other things.

So yea, every person in the trials know there's a chance they're getting a placebo. Anyone taking part who believes everyone is getting the real drug is both deaf and stupid.
post #28 of 94
Quote:
Originally Posted by KittensMewMew View Post

The ethical issues behind testing HIV vaccinations are fascinating. "Here, have an HIV vaccine that we're testing, we don't know if it's 100% effective, but you should have unprotected sex and make as many blood brothers/sisters as possible to see if our vaccine works! Bleed on people! Let them bleed on you! It worked for the guinea pigs, now you get to be the guinea pigs! Science!" I'm glad they have developed a vaccine, but the public backlash against this will be tremendous.
The harshest thing you've ever read.

Volunteers that already live an at-risk lifestyle for exposure to HIV.

Quote:
Originally Posted by matty0610 View Post

Yep that's the problem within those 3 years, those people could die. I would think they would be told to discontinue any current HIV medication so they would be 100% its the vaccine working and not the medicine interfering. Of course they never tell those who are taking the placebo that they are and that they must follow everything the real vaccine takers are doing. Including but not limited discontinuing the meds the are helping them currently.

You guys realized that WITHOUT any sort of drug/treatment, then EVERYONE would die. You don't think that maybe others are willing to risk their lives (which, technically they are already doing by living an at-risk lifestyle) if it helps generate a vaccine? It's not like the people will not be informed of the details and consequences.

No one is forcing people to participate, and these people shouldn't be doing anything different with their lives if they do or don't get a placebo pill. Their biggest danger is their own choices in lifestyle, nothing to do with the drug trial.
Quote:
Originally Posted by bgtrance View Post

Pharmaceutical companies are banking way too much from antiretroviral medications to be allowing cures for such viruses..... mad.gif

It will be interesting what happens in other countries after this trial.
    
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post #29 of 94
T he placebo is there as a method of control. It's a 3 part process

1. The placebo allows the researchers to study cases and the patients condition where the candidate has not gotten the drug.
2. There is sometimes a "mental" effect where if the patient thinks they have received treatment, even though they didn't, their condition will actually improve overtime. (called the "placebo effect"). The inverse of that is patients that may know they are not getting the treatment will sometimes degrade at a quicker rate over time. Thus, you tell them that they are "receiving the treatment" and watch what happens.
3. If the drug has the reverse effect and actually worsens/kills the patients, only half of them will be affected. Thus, even if the drug is a monumental failure, only 50% of participants will be affected.


I urge you guys to read up on this. There's a reason why the idea of a placebo was put in place. Sometimes, an idea can be much more powerful than that of any product.
Edited by Mad Pistol - 2/6/12 at 5:36am
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post #30 of 94
Quote:
Originally Posted by KittensMewMew View Post

The ethical issues behind testing HIV vaccinations are fascinating. "Here, have an HIV vaccine that we're testing, we don't know if it's 100% effective, but you should have unprotected sex and make as many blood brothers/sisters as possible to see if our vaccine works! Bleed on people! Let them bleed on you! It worked for the guinea pigs, now you get to be the guinea pigs! Science!" I'm glad they have developed a vaccine, but the public backlash against this will be tremendous.
The harshest thing you've ever read.

Lol, it's not gonna be like that. More like here is a drug, whether or not it's the vaccine, now go live your life and we shall see you in 3 years. HIV in placebo + No HIV in treatment = working vaccine

Believe it or not there are ethical boards that consider the silly things scientists could do and shouldn't do.
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