ALAS! I have found (at least) a temporary fix, it seems to be a problem with bios settings, this fix will have to be run every time your computer restarts, and it increases your performance by 685%!
I was running everything on low on an AMD Bulldozer 3.60ghz 8 core processor,an Evga Geforce GTX 670 and when I spammed the conference call, it chopped from 50 to 5 frames (literally)
Here is a link to the fix, by the way, my game load time went from 1 and a half minutes, to 9 seconds with PhysX on high, here is the Youtube, and Direct link for the downlaod. Please spread the word, I've had to suffer hours of overnight research, 5 frames on Terramorphous and Hyperius. Post this on every forum and spread the word!
Enjoy Youtube link: http://www.youtube.com/watch?v=nogqQ...eature=related
Direct link to the fix, just run the exe, you must have an amd processor, just a BSOD (Blue screen of death) warning.