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[NIH] Toddler Functionally Cured of HIV

post #1 of 44
Thread Starter 
Quote:
A two-year-old child born with HIV infection and treated with antiretroviral drugs beginning in the first days of life no longer has detectable levels of virus using conventional testing despite not taking HIV medication for 10 months, according to findings presented today at the Conference on Retroviruses and Opportunistic Infections (CROI) in Atlanta.

This is the first well-documented case of an HIV-infected child who appears to have been functionally cured of HIV infection—that is, without detectable levels of virus and no signs of disease in the absence of antiretroviral therapy.

Source: NIH News
Edited by Faraz - 3/3/13 at 2:35pm
Taijin Kyofusho
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Taijin Kyofusho
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post #2 of 44
this is awesome news. Hopefully we'll be able to eradicate this awful virus one day.
Taiga's 2nd wind
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Taiga's 2nd wind
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post #3 of 44
There is a large difference between functionally and fully cured. The child may still be a reservoir, just not actively producing virus now. The issue with removing HIV is that it integrates into the host immune systems DNA.
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post #4 of 44
Thread Starter 
Undetectable viral load after just months of treatment is huge. That it has stayed that way after months of no treatment is even better. The excitement is not over that this child won't transmit the infection to another; it's over the idea that children born to HIV-positive mothers may be cured of the disease themselves. And then there's the prospect of drug-delivery to the child during pregnancy to maybe even avoid infection altogether.
Taijin Kyofusho
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Taijin Kyofusho
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post #5 of 44
Yeah, but it is good news that this kid will hopefully be able to grow up somewhat normally.

I know the other problem with HIV is how rapid it mutates and um...what's the word....i can't think of the word, but within one day HIV spawns several generations worth of it's "family tree" all with different mutations of itself.

that and the whole binding into the dna.
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post #6 of 44
Good now cure cancer
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post #7 of 44
Thread cleaned, and let us hereby declare this thread a 'conspiracy theory-free zone' thumb.gif
    
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post #8 of 44
Quote:
Originally Posted by brettjv View Post

Thread cleaned, and let us hereby declare this thread a 'conspiracy theory-free zone' thumb.gif

Aw man, I got here too late. Let me guess, it was something along the lines of "big pharma's hiding the cure, corporate greed, etc, etc."?
    
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post #9 of 44
I don't know about pharma companies but in the health care setting try our best to control the viral load of the patients. Worst is when the virus becomes resistant and we have to keep switching antivirals, especially due to patient being non compliant with directions and not taking meds.

Like someone mentioned the baby is still host for HIV. Just because the baby has undetectable load at the moment does not indicate that it will shoot back up eventually. Most likely the child will have to be put back on meds. But here's to hoping that child will have good full life and complete treatment become available in the child's lifetime.
post #10 of 44
Quote:
Originally Posted by aroc91 View Post

Aw man, I got here too late. Let me guess, it was something along the lines of "big pharma's hiding the cure, corporate greed, etc, etc."?

Though hardly the right place, it would have been great to read into the tin foil hat brigade lol
    
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