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[NIH] Toddler Functionally Cured of HIV - Page 2

post #11 of 44
Quote:
Originally Posted by fruitflavor View Post

I don't know about pharma companies but in the health care setting try our best to control the viral load of the patients. Worst is when the virus becomes resistant and we have to keep switching antivirals, especially due to patient being non compliant with directions and not taking meds.

Like someone mentioned the baby is still host for HIV. Just because the baby has undetectable load at the moment does not indicate that it will shoot back up eventually. Most likely the child will have to be put back on meds. But here's to hoping that child will have good full life and complete treatment become available in the child's lifetime.

What about the guy who got the marrow transplant from someone with the extremely rare genes that are immune to HIV? (YES I know...it's not a conspiracy). Wonder if there's some way to replicate that.
     
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post #12 of 44
to be honest i couldn't tell you. I'm not specialized in infectious disease nor genetics. Just a lowly pharmacy intern/ resident running various clinics/ go to one when i'm told to. But if you have more info/ link to what you've mentioned I could give my thoughts/ opinions on the topic
post #13 of 44
Quote:
Originally Posted by Rookie1337 View Post

What about the guy who got the marrow transplant from someone with the extremely rare genes that are immune to HIV? (YES I know...it's not a conspiracy). Wonder if there's some way to replicate that.
A gene therapy to give every human CCR5 delta 32 immunity to HIV is still a long ways off.

This child is not carrying HIV btw. Several tests have shown her to have no virus in her bloodstream. She is still shedding viral RNA, but those bits are incomplete and being cleaned out of the early viral reservoirs in her system. She has a viral load of 0, with a 0.000% chance of infecting others. Even a straight injection of her T-cells into another human being would not give that person HIV.
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post #14 of 44
That is good. Even one child that can grow up and live a normal life after HIV is great. I have known way to many friends that have died from this horrible illness.
 
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post #15 of 44
You know I imagine there are a fair number of moral rights issues with human testing, so getting to this point was probably the hardest step. That and the fact of "something that works on an animal, might not work on a human." >.>
     
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post #16 of 44
I heard about this from a friend, pretty great news, but we will have to see if it works in people who are not so young. There is hope!
post #17 of 44
Quote:
Originally Posted by Chakravant View Post

A gene therapy to give every human CCR5 delta 32 immunity to HIV is still a long ways off.

This child is not carrying HIV btw. Several tests have shown her to have no virus in her bloodstream. She is still shedding viral RNA, but those bits are incomplete and being cleaned out of the early viral reservoirs in her system. She has a viral load of 0, with a 0.000% chance of infecting others. Even a straight injection of her T-cells into another human being would not give that person HIV.

So they've pinpointed the gene/mutation? Neat. Still sucks that it's going to be so long until it's actually put in use. Of course I wonder if that whole nanite or simple compound bonding delivery system will be ready sooner. Something about using them to carry a specific payload that only binds to the virus and disassembles it. Hell if I can find the exact link for that though. Keep it up science. Exciting stuff.
     
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post #18 of 44
They will never fully cure HIV, because
Quote:
Originally Posted by Zen00 View Post

The issue with removing HIV is that it integrates into the host immune systems DNA.
HIV is a ticking time bomb that becomes a part of you.

The cure for cancer is much more likely to come before this. Not that it will ever actually happen because companies make too much money watching you die to give you real treatment.
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post #19 of 44
I didn't know that there were people in the world with immunity against HIV. That's very cool.
The stigma about human testing needs to be erradicated. I hear that even if you volunteer, there's still a lot of red tape to go through. It shouldn't be that way.
Edited by xeekei - 3/4/13 at 4:58am
post #20 of 44
Quote:
Originally Posted by Stay Puft View Post

Good now cure cancer

Cancer is a DNA disfunction, I doubt it can be cured like that...


Very, very cool discovery. How long it has been held back, I do not know though.
   
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