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[NIH] Toddler Functionally Cured of HIV - Page 3

post #21 of 44
Im very happy that all the research is actually getting somewhere. How many times have we heard about new treatments being found in some remote forest in Australia and south America etc but you seem to never hear about them again. Same with Cancer research.

But if this is real then it is a great step forward. I just really hope it doesnt financially ruin families in the process you know?

Not everyone has the money that Magic Johnson has.
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post #22 of 44
I applaud the research going to curing HIV, but this is hardly a cure.

First of all. The kid shouldn't have gotten HIV in the first place if the mother took the suggested medication, which has been scientifically show to prevent the transfer of HIV to the fetus. Assuming that every pregnant female with HIV does that, there is no need for the follow up treatment that this child got. This is only useful to babies who have HIV due to the lack of care given by the mother (due to circumstances, with all due respect of course) during the pregnancy and even in that case, blowing a load of different anti HIV pills on the kid, resulting in a one off apparent cure, is hardly scientific or reproducible.
Edited by MoGTy - 3/4/13 at 6:27am
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post #23 of 44
Thread Starter 
Quote:
Originally Posted by MoGTy View Post

I applaud the research going to curing HIV, but this is hardly a cure.

First of all. The kid shouldn't have gotten HIV in the first place if the mother took the suggested medication, which has been scientifically show to prevent the transfer of HIV to the fetus. Assuming that every pregnant female with HIV does that, there is no need for the follow up treatment that this child got.

It wasn't known the mother had HIV until the time of the baby's birth.

And one of the ideas suggested by this case is to be able to prevent infection in the child in the first place by delivering the drugs to it during pregnancy. You're thinking in an ideal world. This is about dealing with reality where you have countless number of adults with HIV who simply will not (cannot, in some countries) acquire treatment and also continue to be sexually active and get pregnant. It's the sad reality.

Quote:
Originally Posted by MoGTy View Post

This is only useful to babies who have HIV due to the lack of care given by the mother (due to circumstances, with all due respect of course) during the pregnancy and even in that case, blowing a load of different anti HIV pills on the kid, resulting in a one off apparent cure, is hardly scientific or reproducible.

Only useful? I think that is quite a large number of babies in certain part of the world we're talking about.

And they didn't "blow a load of different pills". PI and NRTI combination is a cornerstone treatment for HIV. That's what they used. The child is still being followed by an HIV pediatrician so of course his progress will be tracked. If he really is found to never need medications again, this is massive. It is scientific and reproducible.
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post #24 of 44
That very good to know. Its just a matter of time before we get a fully functioning cure. thumb.gif
post #25 of 44
Quote:
Originally Posted by Artikbot View Post

Cancer is a DNA disfunction, I doubt it can be cured like that...


Very, very cool discovery. How long it has been held back, I do not know though.

theyve been using modified virus to kill cancer cells tho.. the dysfunction is in individual cells..
 
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post #26 of 44
Quote:
Originally Posted by Rookie1337 View Post

What about the guy who got the marrow transplant from someone with the extremely rare genes that are immune to HIV? (YES I know...it's not a conspiracy). Wonder if there's some way to replicate that.

Another bone marrow transplant, or possibly extensive gene therapy (but that's a long way off).
Quote:
Originally Posted by Chakravant View Post

A gene therapy to give every human CCR5 delta 32 immunity to HIV is still a long ways off.

And not desirable, as the mutation has a negative effect on T-cell function.
Quote:
Originally Posted by Rookie1337 View Post

So they've pinpointed the gene/mutation?

As of 15+ years ago.
Quote:
Originally Posted by Traphix View Post

They will never fully cure HIV, because
HIV is a ticking time bomb that becomes a part of you.

The cure for cancer is much more likely to come before this. Not that it will ever actually happen because companies make too much money watching you die to give you real treatment.
cigar.gif

Nonsense.

HIV doesn't become a part of you any more than any other retrovirus, and it wouldn't matter if it did, if people had a more effective immune response to it. At any given moment, our bodies are literally awash with and thoroughly permeated by viruses of all sorts, many of them capable of inducing illness in the unhealthy. However, these aren't often a problem in the healthy, nor would HIV be, if, again, one had an effective immune response to it (and some do).

Cancer is a different matter entirely. It's one thing to remove or destroy cancer as you find it, but to completely prevent/eradicate cancer you'd need to make DNA immune to damage and/or be able to rapidly and reliably repair highly unpredictable damage to DNA. Cancer is really broad, and can occur nearly countless ways, in nearly countless types, making it a much more difficult target than any singular, or even any category, of virus caused illness.
Quote:
Originally Posted by Liranan View Post

This 'cure' is nothing but a scam as there is nothing to cure.
Some of the greatest experts in the field say HIV/AIDS is the conspiracy itself and I concur with them, unless this thread has been declared political correctness only.

No credible source suggests anything of the sort., and it's not an issue of political correctness to go where evidence leads rather than giving in to paranoia or burying one's head in the sand to hide from reality.
Quote:
Originally Posted by xeekei View Post

I didn't know that there were people in the world with immunity against HIV.

Nearly 1% of those of northern European descent are nearly completely immune due to having two copies of CCR5-Δ32, which though normally a harmful mutation, is thought to have become prevalent during the Black Death, as there is evidence it protected from that as well. The prevalence of CCR5-Δ32 is good example of natural selection in humans.
Edited by Blameless - 3/4/13 at 7:58am
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post #27 of 44
I don't think this is a cure...they did not treat the baby with anything new. The article lists antiretroviral drugs, It was the same drugs they've been giving to babies (and adults) for while now.

This baby just responded very well to the drugs. If they can find out why and some how induce the same response in other babies it might be something scientifically amazing...as of right now it just falls into the miracle category of really good stuff that happens, but shouldn't have.
Edited by Vagrant Storm - 3/4/13 at 8:06am
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post #28 of 44
Quote:
Originally Posted by Faraz View Post

Well, we don't know how common it is to have newborns initiated on this combination therapy at 30 hours of age so we can't really downplay this just yet. Only a controlled trial of HIV-positive mothers who are about to give birth will settle it for sure.
Why are you not able to post sources for such a bold claim? You say you have sources from "experts". I expect several of them to be posted and they better be reputable and have great peer-review behind them in various scholarly journals. Otherwise, you're looking at a classic loony conspiracy theory here.

Also, source that Magic Johnson does not and did not take HIV medication, please.

Well, any mother that gets prenatal care is given an HIV test. If the mother is positive then the baby is typically tested immediately after birth as well. I certainly haven't researched it, but I find it hard to believe that after they find out the baby is HIV positive the doctors wait a couple weeks to begin treatment. Though maybe they do. Maybe the drugs pose some health risk to a new born and just being HIV positive isn't really a health problem...if AIDS actually fires up then you are in sorry shape, but I am pretty sure that HIV positive people typically don't even know they have it.
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post #29 of 44
The title should read "Toddler accidentally cured of HIV... no one knows how".

I doubt they'll ever figure this one out either, unless the child really was cured by the treatments after birth.
post #30 of 44
Quote:
Originally Posted by Dorkstar View Post

The title should read "Toddler accidentally cured of HIV... no one knows how".

I doubt they'll ever figure this one out either, unless the child really was cured by the treatments after birth.

Exactly, but since everyone on OCN is suddenly a doctor, my mentioning it earlier went up in smoke.
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