Originally Posted by DiGiCiDAL
You aren't going to find an HTPC or desktop orientation case that will have those features. By the time you add in radiator space (or are those going to be purely external) and any decent amount of fans... you've already gotten too large for anything that would be commercially available (at least in a design that fits on your desk). You could custom build one - I've seen a few on here that were scratch builds that basically had the system spread across the entire top of the desk. Or if you want something that's close - you could look at rackmount server cases - and mod as necessary for the cooling side. A decent 4U-5U case would give you the bays, and they are definitely some of the only horizontal cases that can handle an XL-ATX or larger board. (I still think putting a 10-slot case on your desktop is ludicrous, but that's just me).
Even in rackmount server cases - a 10-slot case is a rarity.. at least unless you're talking about passive backplane cases - in which case a 20-slot is available from numerous vendors. I personally think you're much better off either putting a little less hardware in a 'normal' case (CaseLabs new S3
will give you horizontal placement of an ITX board with watercooling, drives, etc... with no issues) and it would fit on a desktop easily (though not under a monitor). With the HTPC cases - I have one of these: LianLi PC-C60
and it's great for a relatively silent air-cooled build... but it certainly isn't going to watercool anything (well not without losing almost all of the hard drive space at least).
So i'm going to build one, I was halfway in the middle of a paint sketchup when i realised "WTH AM I DOING, IVE GOT A TABLET" and i've dusted it off and i've started it, And as for me? i'll probably have it on it's own little desk and once you've gone quadfire you don't go back, That's like going back to a single core