I used to have an eyefinity setup, so I'll weigh in.
First of all, bezels are no problem. The center monitor has your focus, and the side monitors are fully in peripheral vision. I even had a 27'' main screen flanked by 24''s, and the size difference wasn't annoying at all. "Little things" usually annoy me too, but bezels were seriously not an issue in practice.
Gaming wise, it was great for a select few games. The performance drop is fairly large... maybe 50% of a single screen. AA is a huge hog with that many pixels to process. The UI in most games doesn't scale correctly, and the extreme FOV adjustment needed is also not supported by many games. Expect to .ini tweak 90%+ of the games you try and use with triple monitor. RTS games, indie games, etc just don't work at all with eyefinity, as expected. If an FPS supports triple monitor well, it can be a fairly amazing experience.
But in the end I went back to 2 monitors. 3 monitors was too much space for me. I would often get slightly overwhelmed or lose track of windows. I personally prefer dual monitors with Dexpot for multi-desktop switching when it comes to productivity, and in the end a 27 inch monitor is fine for gaming...
Unless you have a specific use for triple monitor, like racing sims/flight sims, I wouldn't really go out of your way to acquire a triple monitor setup. As I said, I actually preferred dual monitor for everyday web browsing and working. Regardless of what you choose, make sure your central screen is high quality. Triple 22'' setups... yeah that seems like a waste to me. A single , bigger, professional quality screen will give a far better gaming experience than that.