I had them or have them all. Really all relevant Mice you can think off and I have fairly big hands too.
From my Experience with those Mice and my past right Hand Project, I would say the G400 is one of the most massive Mice I testet. It has more overall Volume compared to a Deathadder and the same length as a Deathadder or Roccat Kone XTD for example with about 127 mm. But I have to admit controlling a Deathadder gives your more space in terms of grip-possibilites than holding a g400. So grabbing a Deathadder even with big hands is based on your grip cause you could easily almost fingertip it with your half palm and still have a outstanding control where the G400 isn't made for that Type of Grip cause it's more like a truely palmmouse with smaller grip-variation-possibilities.
I have found only one truely great Mouse for my left Hand and a relaxed Palmgrip that's fully enjoyable for a man like me and that's the Razer Boomslang CE 2007 which I got cheap from a austrian Store back in about 2008 or 2009. This is the Mouse I play with right now and I have a awesome relaxed Headaimcontroll and Shotcontrol with it in CSGO.
Good that I bought four Pieces at that Time, cause I still have two Boomslang CE 2007 original sealed in that Collectors Package and two fully functionally used.
The Bomslang CE2007 is the biggest ambidextrous gamingmouse I know in terms of length with about 130 mm and width with about 75 mm and is gold worth for my Situation as a left handed gamer with average big hands.
Not to mention the legendary 3g sensor known from the diamondback 3g is supperb for FPS Gaming.
The Boomslang always was a special Mouse in Terms of Shape and Technic since their very first Ball-Boomslang.
And I am pretty sure Razer will refresh this Mouse at least one time again cause it was their first real legendary gamingmouse dedicatetd to gamers ever. Not only that, from my Informations the Boomslang was THE real very first Gamingmouse recognized on the market ever! Edited by mousefan - 6/15/13 at 4:57pm