There isn't much breathing room in this case for big rads. After all, it is a mid tower. However, I can tell you with a 4770k overclocked to 4.7Ghz with 1.34v, I can still push my classies to 1.35v and 1358Mhz game stable around 40C. 4770k temps are less than ideal, but that's because my block as a stubborn bubble that just won't go away. However, it stays around 65C while gaming.
Keep in mind my cards are as long as a 690 at 11 inches long. Not many cards are this long or longer. (780 Lightning IIRC is the only one that is longer.)
Edited by jameyscott - 11/18/13 at 11:17pm