Originally Posted by El-Fuego
I don't know why some make fun of topics like these, guys please, It's not funny to see a close family member like your father suffer from cancer while you cant do anything!
I really hope they really did make that "wonder" drug,
I get these emails that someone in far place was able to cure HIV and been tested on x number of people and they don't need drugs anymore or someone managed to cure that disease.
I just hope it's true and wish for the best.
Though I strongly agree with the stance that this should not be made a joke out of, regardless of how funny or how well-intentioned it may be. I disagree on simply accepting any given evidence. This field is, or rather can be, incredibly lucrative. Such that if one were to fabricate results they could easily sell them on as a "going concern" if you like, pocketing millions. One such chap did this not too long ago and made of with somewhere in the region of £40million. I shall see if I can dig it up, was a while since I last saw it.
Essentially all I'm trying to say is although we can hope for a miracle cure, we should at least vet it if only for authenticity if not adverse effects.
Originally Posted by jetsam
cd47 is ubiquitously expressed, an anti cd47 antibody will cause autoimmune reactions.
there is no miracle drug for all types of cancers
most likely different cancers and different people will end up having different drugs and combinations of drugs to treat their cancers.
Immunotherapy can do wonderful things, but it will cause serious side effects.
Originally Posted by SectorNine50
This was what I was thinking when I read this... It strikes me that blocking CD47 would cause a lot of friendly fire.
Works quite well on CTLA-4 and PD-L1 though. But yes it does cause autoimmune reactions.Edited by Zorginator - 7/11/13 at 3:55pm