Originally Posted by MonarchX
I had the same exact issue. It was due to Companion-altering mods and due to me setting iPresentInterval=0 (must be set to 1), and IgnoreMouseSmoothing=1 (must be set to 0). Any mod that would allow companions to do things they otherwise could not was causing problems. Having Valentine or other Companion be able to change armor that vanilla game did not allow caused major crashes. I also went through my Textures, Meshes, and Materials folder and made sure there was no junk and no mod's textures overlapped with other mod's textures. Fallout 4 uses up to 6 different texture files for a single textures and its so easy to mix one mod's Normal Maps, for example, with some other mod's Diffuse and/or Specular Maps, let alone mix those with some other mod's Materials and/or Meshes files... Also, there were a few texture mods with fully uncompressed textures that would crash the game completely.
You need to do what I described above to see the approximate cause of the issue. Do this:
- Disable all mods with NMM, start the game, travel to problematic location and see if it crashes, but make sure to test well, not just see if it loads and think you found the problem. If disabling mods fixes the issue, then you need to narrow it down by enabling all mods, disabling top/bottom half, and trying again. If that fails, then its the other half that has the problematic mod, so test a third of those, a 4th, 5th, and then mod by mod.
- If disabling mods does not fix it, rename Textures folder into Textures.org or something and test. If it fixes the problem, then test each Textures sub-folders like you did with mods (halves, thirds, etc. until you have to try folder by folder, and then file for file). This can take a LOOONG time.
- If Textures folder renaming to Textures.org did not help, then rename Interface to Interface,org and test, then Music to Music.org and test. Do it for ALL the Data folders and if one resolved the issue, narrow it down to specific files.
- Finally, if the 2 solutions above do not work, then delete all your Fallouts4.ini, Fallout4Custom.ini, and Fallout4Prefs.ini and test the game. WARNING, this should be the last solution because lowering uGridsToLoad alone can create an impression of the issue being fixed, but it is the unlikely cause. Higher uGridsToLoad loads bigger areas, some of which will not be loaded if you use lower uGridsToLoad and stand in the same location. To test, make sure to explore more areas, travel more, etc. Lower uGridsToLoad always made the game more stable, BUT it would still crash.
- If all above fails, remove ENB and/or ReShade entirely and test it.
***TEST THOROUGHLY***. Load the problem area and spend good 5-10 minutes exploring it, saving and reloading.