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post #311 of 480
Quote:
Originally Posted by looniam View Post

if you didn't eat, just take some B1 and you'll have no worries. thumb.gif
That and B3 are only side effects. Not even the main harm from acetaldehyde.
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post #312 of 480
Quote:
Originally Posted by mtcn77 View Post

Quote:
Originally Posted by looniam View Post

if you didn't eat, just take some B1 and you'll have no worries. thumb.gif
That and B3 are only side effects. Not even the main harm from acetaldehyde.
niacin has nothing to do with it.

since you didn't bother to find out the cause of your pretty pictures:
Quote:
People who have been drinking large amounts of alcohol for long periods of time run the risk of developing serious and persistent changes in the brain. Damage may be a result of the direct effects of alcohol on the brain or may result indirectly, from a poor general health status or from severe liver disease.
For example, thiamine deficiency is a common occurrence in people with alcoholism and results from poor overall nutrition. Thiamine, also known as vitamin B1, is an essential nutrient required by all tissues, including the brain. Thiamine is found in foods such as meat and poultry; whole grain cereals; nuts; and dried beans, peas, and soybeans. Many foods in the United States commonly are fortified with thiamine, including breads and cereals. As a result, most people consume sufficient amounts of thiamine in their diets. The typical intake for most Americans is 2 mg/day; the Recommended Daily Allowance is 1.2 mg/day for men and 1.1 mg/day for women (14).
Wernicke–Korsakoff Syndrome

Up to 80 percent of alcoholics, however, have a deficiency in thiamine (15), and some of these people will go on to develop serious brain disorders such as Wernicke–Korsakoff syndrome (WKS) (16). WKS is a disease that consists of two separate syndromes, a short–lived and severe condition called Wernicke’s encephalopathy and a long–lasting and debilitating condition known as Korsakoff’s psychosis.

there you go. it is a poor diet not the actual consumption of alcohol that is what you saw. if you had bothered reading the link - from the national institute of alcohol abuse and alcoholism - it is the life style of excessive drinking over a period of years.[/B]

rule 1 of scientific inquiry: correlation does not equal causation.

an alcoholic having brain damage doesn't mean it was caused by alcohol. being an alcoholic myself - it behooves me to find out everything about my condition i can.

this isn't a pissing contest.
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post #313 of 480
Quote:
Originally Posted by looniam View Post

possibly, since i have a bit of "wet brain" myself from 30+ years of alcohol abuse followed by 10+ years of sobriety (i'm 53)

so please tell me how you looking at one finding with some pretty pictures will give me or anyone more information about a medical condition i have then the several professionals i have seen in the last decade?

you are completely out of your league - this is not a game of your usual "one upmanship" move on.
Your health contingencies do not make up for good example then. I'm sorry, but I wish you good health!
This is from the clinical textbook of neurology. Vitamin B3 (Click to show)
Quote:
METABOLIC DISORDERS: 1. ALCOHOLISM Certain complications of alcoholism can cause dementia. These include acquired hepatocerebral degeneration from alcoholic liver disease, chronic subdural hematoma from head trauma, and nutritional deficiency states.
Pellagra:, caused by deficiency of nicotinic acid (niacin), affects neurons in the cerebral cortex, basal ganglia, brainstem, cerebellum, and anterior horns of the spinal cord. Systemic involvement is manifested by diarrhea, glossitis, anemia, and erythematous skin le-sions. Neurologic involvement may produce dementia; psychosis; confusional states; pyramidal, extrapyramidal, and cerebellar signs; polyneuropathy; and optic neuropathy. Treatment is with nicotinamide(B3), but the neurologic deficits may persist despite treatment.
Vitamin B1 (Click to show)
Quote:
NUTRITIONAL DISORDERS WERNICKE: ENCEPHALOPATHY Wernicke encephalopathy is usually a complication of chronic alcoholism, but also occurs in other disorders associated with malnutrition. It is caused by deficiency of thiamine (vitamin B 1). Pathologic features include neuronal loss, demyelination, and gliosis in periventricular gray matter. Proliferation of small blood vessels and petechial hemorrhages may be seen. The areas most commonly involved are the medial thalamus, mammilary bodies, periaqueductal gray matter, cerebellar vermis, oculomotor, abducens, and vestibular nuclei.
That is the big holes in the middle and anything surrounding it.
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post #314 of 480
Looks like the game runs really well maxed out on a 290X without Hairworks. Tha'ts good enough for me. But I surely will be turning a few options down to get 40+fps @1440p biggrin.gif
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post #315 of 480
I got your back Looniam. I have experience in the field of addiction treatment, on both sides of the desk, and I am a Psychopharmacologist so I feel myself to be fairly knowledgeable on the subject, and EtOh doesn't dissolve your brainstem any more than LSD stays in your cerebrospinal fluid forever.

Nice try, please play again!
   
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post #316 of 480
Quote:
Originally Posted by mtcn77 View Post

Your health contingencies do not make up for good example then. I'm sorry, but I wish you good health!
This is from the clinical textbook of neurology. Vitamin B3 (Click to show)
Quote:
METABOLIC DISORDERS: 1. ALCOHOLISM Certain complications of alcoholism can cause dementia. These include acquired hepatocerebral degeneration from alcoholic liver disease, chronic subdural hematoma from head trauma, and nutritional deficiency states.
Pellagra:, caused by deficiency of nicotinic acid (niacin), affects neurons in the cerebral cortex, basal ganglia, brainstem, cerebellum, and anterior horns of the spinal cord. Systemic involvement is manifested by diarrhea, glossitis, anemia, and erythematous skin le-sions. Neurologic involvement may produce dementia; psychosis; confusional states; pyramidal, extrapyramidal, and cerebellar signs; polyneuropathy; and optic neuropathy. Treatment is with nicotinamide(B3), but the neurologic deficits may persist despite treatment.
Vitamin B1 (Click to show)
Quote:
NUTRITIONAL DISORDERS WERNICKE: ENCEPHALOPATHY Wernicke encephalopathy is usually a complication of chronic alcoholism, but also occurs in other disorders associated with malnutrition. It is caused by deficiency of thiamine (vitamin B 1). Pathologic features include neuronal loss, demyelination, and gliosis in periventricular gray matter. Proliferation of small blood vessels and petechial hemorrhages may be seen. The areas most commonly involved are the medial thalamus, mammilary bodies, periaqueductal gray matter, cerebellar vermis, oculomotor, abducens, and vestibular nuclei.
That is the big holes in the middle and anything surrounding it.

you need to go up one post from this.

and i am not going to entertain your fishing expedition - as i said before you have no idea what you're talking about and i see no reason to carry this any farther esp on this thread.

but thanks for wishing me well. thumb.gif
Quote:
Originally Posted by nleksan View Post

I got your back Looniam. I have experience in the field of addiction treatment, on both sides of the desk, and I am a Psychopharmacologist so I feel myself to be fairly knowledgeable on the subject, and EtOh doesn't dissolve your brainstem any more than LSD stays in your cerebrospinal fluid forever.

Nice try, please play again!

the doctor is in.

lachen.gif
Edited by looniam - 5/18/15 at 8:21pm
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post #317 of 480
I can't be bothered to list all of the different effects alcohol has on the brain. Anyone who still thinks otherwise has already decided to reject any evidence that contradicts their beliefs, because at this point it is just a personal belief with no foundation in reality.

http://en.wikipedia.org/wiki/Long-term_effects_of_alcohol_consumption

It's sufficient to say that you don't get 181 citations of medical studies of the detrimental effects of long term alcohol consumption for being mostly harmless.

http://en.wikipedia.org/wiki/Long-term_impact_of_alcohol_on_the_brain

Some more technical references listed there. Have a good evening folks, and let's put this thread back on topic.
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post #318 of 480
Well I could certainly use some alcohol after reading the last 20 posts lachen.gif
post #319 of 480
Edit: Wrong thread, sorry
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post #320 of 480
It does NOT "dissolve" nervous tissue, period!

I am not saying it's healthy, but this is the 80's "just say no"/"addiction is a weakness of character/the soul" FUD I got into the field to help quell the spread of further falsehoods.
   
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LG/Hitachi Slim DVD-R/W Custom MB-Backside VRM-sinks (Copper) 3x NZXT RF-FX140LB 1-2krpm 98.3CFM Case Fans 2x Corsair SP120-PE Case Fans 
CoolingCoolingCoolingCooling
Heatkiller GTX680 "Hole Edition" Block + Backplate XSPC Single-Bay Res (Single 5.25 bay) EK Multioption Res X2 - Advanced 150 DD "Fill-Port Res" + Fill-Port Fitting (Red) 
CoolingCoolingCoolingCooling
2x MCP35X + Heatsinks/80x15mm Fan XSPC EX420 Alphacool NeXXos UT60 240 6x Bgears Blasters 140mm 1800rpm Fans 
CoolingCoolingCoolingOS
4x Koolance 120x25mm 2600rpm Fans Comp/Rotary Fittings (BP/XSPC/Monsoon) Primoflex Pro LRT - White (1/2x3/4) Windows 7 Professional 64bit  
MonitorMonitorMonitorMonitor
Dell P2210Hb 21.5" 1920x1080p Viewsonic VA2012WB 20.1" LCD 1680x1050 Dell U3014 Eizo 27" 1440p 10bit RGB-LED Backlit AH-IPS Panel 
MonitorKeyboardPowerCase
55" LG HDTV (their top 2014 model) Ducky Mechanical (Browns) NZXT HALE90 850W + 8 blown-up AX1200/i's NZXT Switch 810 (White) 
MouseMouse PadAudioAudio
R.A.T.3 + MX510 My Desk GRADO RS1i Headphones Grado PS1000 Headphones 
OtherOtherOtherOther
Bitfenix Hydra Pro Fan Controller 5ch 30W/ch Bitfenix Alchemy Individually-Sleeved Extension... NZXT Individually-Sleeved Front Panel Wires (Bl... Phobya Sleeved 1x3pin-to-4x3pin Fan Splitter 
OtherOtherOther
Sleeved Wires w Paracord myself (no Heatshrink) Custom Front and Top Panels w HexxMesh *In Prog... Working on Custom Pedestal Prototype 
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Z77 Bench-a-lot
(31 items)
 
CPUMotherboardGraphicsGraphics
i7 3930K @ 4.92Ghz Asus Rampage 4 Extreme EVGA GTX670 FTW 2GB  EVGA GTX780Ti Classified K|ngp|n Edition @ 1483... 
GraphicsRAMHard DriveHard Drive
EVGA GTX780Ti Classified K|ngp|n Edition @ 1483... 16GB G.Skill Ripjaws-Z @ DDR3-2248 9-10-9-26 1T Samsung 830 256GB SSD WD10EZEX 1TB HDD 
Hard DriveHard DriveHard DriveHard Drive
WD10EALX 1TB HDD Seagate Barracuda 7200.14 1TB WD3200AAKS 320GB HDD WD5000HHTZ 10krpm 500GB VelociRaptor 
Optical DriveCoolingCoolingCooling
LG/Hitachi Slim DVD-R/W Custom MB-Backside VRM-sinks (Copper) 3x NZXT RF-FX140LB 1-2krpm 98.3CFM Case Fans 2x Corsair SP120-PE Case Fans 
CoolingCoolingCoolingCooling
Heatkiller GTX680 "Hole Edition" Block + Backplate XSPC Single-Bay Res (Single 5.25 bay) EK Multioption Res X2 - Advanced 150 DD "Fill-Port Res" + Fill-Port Fitting (Red) 
CoolingCoolingCoolingCooling
2x MCP35X + Heatsinks/80x15mm Fan XSPC EX420 Alphacool NeXXos UT60 240 6x Bgears Blasters 140mm 1800rpm Fans 
CoolingCoolingCoolingOS
4x Koolance 120x25mm 2600rpm Fans Comp/Rotary Fittings (BP/XSPC/Monsoon) Primoflex Pro LRT - White (1/2x3/4) Windows 7 Professional 64bit  
MonitorMonitorMonitorMonitor
Dell P2210Hb 21.5" 1920x1080p Viewsonic VA2012WB 20.1" LCD 1680x1050 Dell U3014 Eizo 27" 1440p 10bit RGB-LED Backlit AH-IPS Panel 
MonitorKeyboardPowerCase
55" LG HDTV (their top 2014 model) Ducky Mechanical (Browns) NZXT HALE90 850W + 8 blown-up AX1200/i's NZXT Switch 810 (White) 
MouseMouse PadAudioAudio
R.A.T.3 + MX510 My Desk GRADO RS1i Headphones Grado PS1000 Headphones 
OtherOtherOtherOther
Bitfenix Hydra Pro Fan Controller 5ch 30W/ch Bitfenix Alchemy Individually-Sleeved Extension... NZXT Individually-Sleeved Front Panel Wires (Bl... Phobya Sleeved 1x3pin-to-4x3pin Fan Splitter 
OtherOtherOther
Sleeved Wires w Paracord myself (no Heatshrink) Custom Front and Top Panels w HexxMesh *In Prog... Working on Custom Pedestal Prototype 
  hide details  
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