Originally Posted by SabbathHB
I use a fairly large air compressor myself and as long as you're somewhat careful you should have no problems. I'd be careful using a vacuum to clean it inside the case. They can easily cause a static charge. Also if you use compressed air make sure you don't let the fans spin, it can damage them.
If sucking air causes static so would blowing air, the only time it becomes an issue is in dry climates. If you mean static build up in the nylon vacuum "wands" again you would need to be vacuuming for hours and hours to build up enough charge to make it arc. Plus nylon is an insulator in most solid forms, you know like those old plastic standoff people loved before they realized they can cause weird grounding feedback loops by not completely ground the motherboard.
Just don't use it directly on your cpu cooler(while mounted to your cpu) your gpu's cooler(while mounted to your gpu) or your ram or pci-e slots and you'll be pretty fine everything else can take a little bit of static build up the whole thing is grounded after all.
Honestly I'm a bigger fan of leaf blowers than vacuums, but using a vacuum outside of your case and the bottom of your case, and using the leaf blower on the rest. A leaf blower can be had for $40 and you don't need to worry about drying the air like you would with a compressor, a compressor is at least $100 and you need to add an air drier to it to make sure you don't blow water or oil(oh a lot of cheap compressors will spit out oil into the compressed air it's a big problem for people using them to paint with) I don't think it's worth it.