It has been smooth sailing, did not really have any oh **** moments. TBH, the build process is quite simply a few holes here and there. Most of it is thought out way before purchasing any parts.
Air flow is absolutely horrible, I have 3 low speed (i'm talking really low: 400rpm) fans blowing down into the case for positive pressure, and no extract fans. CPU/GPU temps are not bad at 65/55c load respectively, but the aluminium case does get warm to the touch.
Clocks are i7 6700k @4.7 with 1.4V, and 1070 @2138 no extra voltage BTW
I'm thinking of reversing the fans for negative pressure and just deal with the dust, i.e. how lian li designed it to work. All the PCBs are up right so no place for any dust to settle, hopefully not too difficult to clean regularly.
The NZXT version of the asetek AIO has pretty long hoses, and should be able to be tucked away behind the ledge above the motherboard i/o, i use that ledge to hide the LED strip. I would look for the longest hose possible if your going that route, may get lucky and be able to hide hoses behind the motherboard. But the HG10 would look kind of ghetto, as it is in full front view and not that aesthetically appealing imho.