I have never been a fan of AMD Chipsets. I used to LOVE their CPUs but hated using VIA or AMD based chipset motherboards. I have to admit that the 990FX changed my view a tad but it is still delivering subpar USB/PCIe and I/O performance when compared to an Intel equivalent chipset.
Another thing which irks me is the lack of a decent Gigabit (or higher) NIC being integrated onto AMD platforms. I despise and loathe Realtek based chips as I find them to produce rather bad results. Under intense stress... I have had quite a few Realtek Integrated NICs simply fail (particularly on Gigabyte motherboards).
The Realtek audio is another point of contention. I think that if AMD is to release a full platform... they need to work on the platform itself, not just the CPU. It would be nice if TrueAudio was integrated onto the motherboard but not by using anything Realtek related. Maybe a C-Media Oxygen HD chip instead. Something which screams "High quality gaming platform".
For the NIC... if I were AMD... I would focus on convincing my motherboard partners into using Intel chips for the task (unless AMD opts to develop their own killer NIC chip). Realtek is really "THAT BAD".
I am pretty sure I am not the only one who has had to suffer the cheapness of Realtek based products. Anytime I see a nice and shiny Asus Rampage X Extreme motherboard with realtek components... I die a little inside.
The first thing I did once I bought my Asus Rampage IV Extreme motherboard was to disable the Realtek audio and use this instead...
On my AMD boxes, I have used Auzentech X-Fi Prelude 7.1 and Forte sound cards (varying on if there was a PCIe or PCI slot available). Realtek just really sucks and sounds like you're listening to music/movies/video games from within a tin can the moment you buy a pair of high-grade headphones (like Sennheiser etc).