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[ScienceDaily] Naked mole-rats 'turn into plants' when oxygen is low - Page 2

post #11 of 24
Quote:
Originally Posted by KaffieneKing View Post

Talk about click-bait!

Using metabolic pathways associated with plants does not make one a plant...
You know everyone talks about how we share so much DANA with other animals. I wonder how much we do share with plants.
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post #12 of 24
Naked mole rats also are resistant to developing cancer even if you put cancer cells in them they still won't get it. That was being studied at my job. Naked mole rats are pretty interesting animals in how they live in a hive with workers and queens, and how ugly they are.
post #13 of 24
Quote:
Originally Posted by New green View Post

I had to post this video. Something I've seen awhile ago and had to share. Reading the article now.

Edit:

"In the new study, the researchers exposed naked mole-rats to low oxygen conditions in the laboratory and found that they released large amounts of fructose into the bloodstream. The fructose, the scientists found, was transported into brain cells by molecular fructose pumps that in all other mammals are found only on cells of the intestine." https://www.sciencedaily.com/releases/2017/04/170420141844.htm

These fructose pumps in naked mole rats were found in their brain cells and heart cells. https://www.youtube.com/watch?feature=youtu.be&v=6DHErT2--E4

I also found this. Humans apperantly don't have these fructose pumps to actually feed our brains cells, but fructose can be produced in the human brain.

"“In this study, we show for the first time that fructose can be produced in the human brain,” said first author Dr. Janice Hwang, assistant professor of medicine.

While the production of fructose in the brain had been seen in animals, it had not been demonstrated in humans, Hwang noted." http://news.yale.edu/2017/02/23/fructose-generated-human-brain

"The current data demonstrating that fructose is produced in the human brain in response to hyperglycemia via the polyol pathway activity as well as evidence for the presence of aldose reductase, the rate-limiting enzyme in the polyol pathway, throughout the human brain, particularly in the cerebral cortex, basal ganglia, and hippocampus (11), may have particular implications for disordered eating behavior and disordered cognition in patients with diabetes." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313070/#!po=30.9524
Nice Vid, Thanks for sharing thumb.gif
Quote:
Originally Posted by DVLux View Post

This thread title is *completely* misleading. doh.gif

Quote:
Originally Posted by mrawesome421 View Post

Yeah no kidding.

I read the thread title and the first thing my brain came up with is a hairless rat that somehow morphs into a house plant... blinksmiley.gif
haha +1 I thought so too. biggrin.gif
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post #14 of 24
Yeah, but how long can they live when clothed?
post #15 of 24
Quote:
Originally Posted by steadly2004 View Post

You know everyone talks about how we share so much DANA with other animals. I wonder how much we do share with plants.

In short we share the most similarities with other animals, then fewer DNA similarities with eukaryotic organisms such as plants, and even fewer with bacteria and archaea.

In my opinion it is more likely that plants and the naked mole rat co-evolved this metabolic pathway, instead of having a more closely shared ancestry. Such as how dolphins and most fish have similar traits, due to evolving in similar conditions thus both having fins and skin that easily blends in with the sea. In the case of the naked mole rat and plants, the condition was low oxygen levels.

Hope this helps a bit haven't done anything but human or bacterial biology in years!
Edited by KaffieneKing - 4/24/17 at 12:38pm
post #16 of 24
But how do you overclock it?
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post #17 of 24
Quote:
Originally Posted by MDalton10 View Post

But how do you overclock it?

slap a waterblock on it and Mole rat boost 9.0 will automatically overclock it to 9999GHz thumb.gif
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post #18 of 24
Quote:
Originally Posted by MDalton10 View Post

But how do you overclock it?

"Fructose transport across cell membranes is carried out by members of the facilitated glucose transporter (GLUT, SLC2) family. Among the 14 members of human GLUT protein family, only GLUT5 is fructose specific and lacks the ability to transport other carbohydrates such as glucose and galactose5,6,7. GLUT5 is expressed in intestinal epithelia, sperm, brain, fat, skeletal muscle and kidney cells8.

Given the medical importance of GLUT5, its inhibitors could potentially serve as therapeutics for the treatment and management of cancer or diabetes. Nonetheless, selective and potent inhibitors for GLUT5 have not been described. Despite the high sequence similarity among GLUT members, known inhibitors of other GLUT proteins (for example cytochalasin B, phloretin, or forskolin) do not affect GLUT5, suggesting that subtle differences may be responsible for ligand specificity among GLUT family members (this work,17,18). Indeed, a recent study found two natural products that inhibit GLUT5; one of which, rubusoside, a natural sweetener from the Chinese sweet tea plant (Rubus suavissimus), inhibited both GLUT1 and GLUT5, the first example of a common inhibitor for these two GLUTs. The other molecule, astragalin-6-glucoside, a flavonoid compound from the American pokeweed (Phytolacca americana) did not affect GLUT1. These inhibitors, though not potent (IC50 values ~ 5 mM) allowed for the identification of active site differences between GLUT1 and GLUT5 responsible for ligand specificity17." https://www.nature.com/articles/srep24240
post #19 of 24
Quote:
Originally Posted by Ganf View Post

Quote for the ages...

"If you ever wondered what a real super hero looks like, it looks like this....

Like a Ball Sack...."
*watches YT vid*
*looks down at the boys*

Yup thumb.gif
post #20 of 24
Quote:
Originally Posted by philhalo66 View Post

Who would have thought Rufus would have been so useful outside of saving the world. wink.gif

Dreaming about teenage action heroes today? rolleyes.gif
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Overclock.net › Forums › Industry News › Technology and Science News › [ScienceDaily] Naked mole-rats 'turn into plants' when oxygen is low