The Cosmos positions the power supply at the bottom, albeit not in a separate compartment (there's just a duct sitting next to the graphics card area). Cooler Master is being a little creative with airflow, though: the case will have negative pressure by default, with the only intake fan (a 120mm model) positioned at the bottom. One 120mm exhaust fan is located at the rear, and a couple of 120mm exhaust fans sit at the top of the case. The Cosmos also has holes at the back to accommodate a liquid cooling system, and the case's side panels are padded with sound-insulating foam. But even with Cooler Master's emphasis on low noise levels, the case is sufficiently ventilated to handle a pair of GeForce 8800 graphics cards.
In fact, Nvidia had a version of the the case on display running a pair of GeForce 8800 Ultra graphics cards—a testament to the case's cooling abilities. The Cooler Master Cosmos is scheduled to hit stores in August with a price tag in the $200-220 range.