Yes it does but with your processor you should be using Prime95 v25.6 (and only this verison or later)
Orthos does not officially support quads, you will need to run two instances which can cause errors even on a stable OC.
EDIT: There is no reason to run 4 instances of this. This version will automatically detect your cores and launch the threads needed.
Interesting I didnt know that about orthos. Thanks