Originally Posted by reezin14
Have you taken a look at BitLocker Drive Encryption,I haven't personally used it but it seems like it will do what you need.
It's fairly simple. What i would do is for each of the shared drives go in and modify the access to that drive for "authenticated users" this will allow anyone who knows the username and password for the server to access the drives. Then take the single HDD and give it permission for only you.
All you need for this to work is for the Server to have atleast 2 user accounts. 1 for users (DO NOT give it admin rights, user or power user is enough) and then a 2nd account for you, with admin rights.
Once you've set the 5th HDD to only be accessible via your login it will be secured, and since the 2nd account is not an admin they can't go changing permissions.