Just picked up my Saitek Cyborg RAT7 today at Fry's. Just for giggles, I also shelled out an extra few bucks for the Saitek Cyborg RAT pad as well.
The first thing I noticed about the RAT is just how heavy it is. Even after removing nearly all the weights, it's still much heavier than my old POS Logitech mouse. I pick up and move my mouse a lot, and the weight of this thing is definitely going to take some getting used to. I'm also used to having my button fingers closer together, so it's a little difficult adjusting to that as well. Fingers are getting a little cramped; but I'm sure I'll adjust in time.
Tried out the wide pinky rest, but it did't really feel very comfortable, so I went with the rubberized one. More comfy, and the stickiness helps when I pick up and move it. I really like the palm rest; but I think I'm going to switch to the rubberized one there as well. Still trying to get some of the adjustments right; but overall I'm certain that I'll like this a lot once I do get it adjusted. It's certainly one of the most well-constructed pieces of computer hardware that I've ever owned. The large scroll wheel is very nice.
The Cyborg pad is also nice. It's very solid, being mainly a big chunk of machined aluminium plate. There are two surfaces applied to the metal, one very fine, and one coarser; which the describe as "high precision" and "high speed" respectively. So far I've only used the finer one, and I definitely like it. Sticky feet at the corners keep it solidly anchored.