Frustrating. It would bother me not being able to get it to work. Honestly though other than for benchmarking overclocks (4.6 or so) I've found 22 to be pretty worthless and I think most would agree. My CPU simply likes 21 better and I can get it stable at lower voltages. Some have found 20 works for them. I understand your RAM issue and sometimes you just have to work with what you have. I'd probably still keep messing with it untill I found a way or drove myself crazy
crazier. I think intel requires the BIOS makers to make it a PITA to use certain features that they would rather require to have only available at stock. Usually there is a way though and it just takes some tinkering to figure out how they back doored it in.
You might have to back off the memory multi to 2:6 and try out something like 211 X 19, or 201 X 20.
(sorry reading comprehension problems today apparently) From my own testing with 3D benchies I'd take a lower memory frequency over a lower CPU frequency. In the testing I did 150Mhz made zero difference at the same CPU clock. If you were all that worried about 2D benchies (which the memory frequency can make a significant difference) you'd already have the higher frequency memory. Everyday use and average gaming though you won't see much difference other than the higher memory frequencies always just "feel" snappier to me on the desktop but that is hard to quantify outside of maybe SuperPi.
Of course maybe with a little voltage and timing adjustment you'll be able to hit 1600Mhz after all anyway making it a non issue. Try getting stable with 191 baseclock and the 2:6 multi then going back and lowering the baseclock changing the multi to 2:8 then walk the baseclock up. Try 1.64v-1.66v Dram Voltage and 9-9-9-24 or looser timings. Alot of times the only difference between some sticks that are speced with different frequency or timings is the recomended Voltage. Of course try at your own risk