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post #101 of 133
Almost all of the papers the Pande group has produced are in top-tier journals (EF98+), some in the most influential journals in the world. For example, PNAS rejects IIRC 95% of all submissions). Most of them have quite a few cites, some being cited hundreds of times by other scientists.

For a fairly esoteric subject area like computational molecular dynamics (how many people carry a tflop in their back pocket), that seems very impressive.
post #102 of 133
Quote:
Originally Posted by r31ncarnat3d View Post
How so? Protein folding is an integral yet very little understood part of molecular biology. Every organism depends on proteins to survive and yet we practically do not have any existing models of the protein folding itself. It's a highly complex interaction of hydrophobic, hydrophilic, and electron charge-based interactions and isn't as simple as most people would like to believe. Then there's the fact that many diseases affecting primarily elders, including Alzheimers and Parkinson's, as well as genetic diseases like Huntington's, are all affected by misfolding proteins. Even as little as one misfolded protein is enough to cause aggregates to form and cause correctly-folded proteins to be misfolded, leading to the crippling diseases you see.

A model of protein folding could help us better understand folding and from there, help us figure out a cure where we could "chaperone" misfolded proteins into their proper conformations or even learn how to prevent misfolding from occurring, esp in those with a genetic disposition to do so.

It's an extremely subtle science, but anyone in biomedical research or molecular/cellular biology will tell you this is an astounding step forward. Many people, esp those outside the upper echelons of biology won't understand the significance of Folding @ Home but that's not to say that the significance isn't there.
How many cancer patients own a microwave, cellphone, or car. How many live near microwave antennas, toxic dumps and industrial pollution ? How many have a meat/GMO base diet ? Why don't we ever hear these numbers ?

Quote:
Originally Posted by Raul-7 View Post
It's major fallacy to assume pharmaceutical companies want to cure cancer.

Treating the symptoms makes more profit than curing the disease.
Funny how we have no probs finding better ways to destroy and/or poison ourselves and the environment.

Peace
post #103 of 133
Quote:
Originally Posted by Hickeydog View Post
I get a space heater for my room. And it cures cancer. Win-win.
i live in the basement of my house and its cold in the winter the space heater i have is about twice the cost of my computer... and my pc warms the entire house XD
post #104 of 133
its for a good cause. if you want to do good things then fold cause itll save lives one day since research funding is always so limited
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post #105 of 133
if u fold long time, wont the radiation from electricals in the pc gets to you and get you cancer?

    
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post #106 of 133
Quote:
Originally Posted by Khaotik55 View Post
I find folding stupid and pointless. It doesn't help jack imho.
Why do people say "imho" about things that are not a matter of opinion?
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post #107 of 133
Quote:
Originally Posted by jy360 View Post
asking why people fold is much like asking why people give to charity, it can also be considered a waste
Good point. Rep+
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post #108 of 133
Quote:
Originally Posted by Raul-7
It's major fallacy to assume pharmaceutical companies want to cure cancer.

Treating the symptoms makes more profit than curing the disease.
So much pessimism!

Trust me, EVERYONE would like to be the one to discover the cure to cancer. They would be a national, and world-wide hero. There might be a few insanely greedy people who wouldn't want it because it would kill their business, but the vast majority of people in the medical and scientific world LOVE to help people - that's why they are in those fields in the first place, to help people.

EDIT: And on that note, I'm going to go invent a space-heater that gets heat from folding... brb, going to find out which processor can stand the most heat, and how many I can put on the same motherboard.
post #109 of 133
Quote:
Originally Posted by DEC_42 View Post
As for the OP, who clearly just started this thread to get attention, Folding@Home is more constructive for society than letting your computer idle until you feel like shooting something or jacking off.
Well, with that, I'm sold. This gives me a selfless explanation for my computer's existance! I've been building a rig since June, and recently bought a GTX 570. I can fold now, and I think I will. I'm very discouraged by many of the narrow-minded and short-sighted posters in this thread, though they don't make up nearly a majority of the people here. The goal of Folding@Home isn't so that you can claim that your personal computer cured cancer. It's about doing something small to help advance medical research. The contribution is so minor as to be negligible, and considering I don't pay for my utilities (they're included as a fixed amount in my rent) I'm kind of ashamed that I'm only starting to fold now.
post #110 of 133
Quote:
Originally Posted by Magikherbs View Post
How many cancer patients own a microwave, cellphone, or car. How many live near microwave antennas, toxic dumps and industrial pollution ? How many have a meat/GMO base diet ? Why don't we ever hear these numbers ?
Does not see the relation between this and my post.
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