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post #91 of 133
Quote:
Originally Posted by r31ncarnat3d View Post
Because I'm a molecular biology student and I have both worked with and had family members inflicted by prion-induced diseases.




Wrong. Cancer is a mutation within our DNA that causes our cells to revert to embryonic-stage development in terms of genetic expression. Man-made causes are definitely a very large factor in inducing these mutations, but there are natural causes as well. Cancer is not man made.

Also wanted to add:

Folding @ Home is a distributive project researching protein folding. This means that potential disease cures only will be in diseases that are a result of misfolded proteins. This means that cancer, AIDs, and viral/bacterial infectious diseases will probably not benefit from Folding @ Home.

It's a great cause, but just wanted to get that straight. Anyone from OT probably saw this post coming from me.
My understanding, is that cells that become cancerous fail to be shutdown due to protein misfolding, at lest certain forms of cancer anyhow. So it does relate back. I'm not sure how things like Influenza relate back to protein misfolding.
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post #92 of 133
Quote:
Originally Posted by Skripka View Post
My understanding, is that cells that become cancerous fail to be shutdown due to protein misfolding, at lest certain forms of cancer anyhow. So it does relate back. I'm not sure how things like Influenza relate back to protein misfolding.
Of course, I'd definitely like to be proven wrong here (I'm a bio nerd this way).

My understanding is that protein misfolding is an indirect result (or rather, intermediate) of it. Rather, mutations within the DNA changes the mRNA and subsequently the primary structure of an important protein, and either the lack of properly folded protein itself leads to cancer. This is different from TSEs where misfolded proteins come from properly coded DNA (meaning something went wrong in the mRNA -> Protein translation phase) and cause other properly folded proteins to become misfolded themselves in a cascading reaction, all the while leaving the genome unchanged/unmutated.

Again, if anyone has information saying otherwise, I'd like to be proven wrong on this
post #93 of 133
I'm very new to folding. Other than leaving my PC on 24/7, which is obvious, how can I increase my folding numbers? Using my sig rig that is.
post #94 of 133
To get back to the OP's orignal question of why I fold....

Like so many things I do, its because i want too.

The reasons have generally been covered, so I wont bore everyone with them again.

Is it me or is there a general troll fest going on with Folding and Boinc ATM? If there is, its getting real old, real fast.
post #95 of 133
Because they can and it doesnt hurt
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post #96 of 133
Quote:
Originally Posted by taystew View Post
waitwaitwait. folding has actually cured people? i cant find any evidence of this.
No cures yet, but there is research into cures and protein folding directly drawing off of the F@H data.


Quote:
Originally Posted by Khaotik55 View Post
I don't want to sound like a self-centered ass wipe, but I've always wondered the same thing. I find folding stupid and pointless. It doesn't help jack imho.
Which is why I know you've never been involved in biomedical research
post #97 of 133
Quote:
Originally Posted by r31ncarnat3d View Post
No cures yet, but there is research into cures and protein folding directly drawing off of the F@H data.


Which is why I know you've never been involved in biomedical research
You my friend, suffer fools much better than I.
post #98 of 133
Quote:
Originally Posted by zorrobyte View Post
A flip side, I'm not too happy about the state of the medical industry (as there is no money in a cure, only treatment) and there has been no harm experimental treatments (oxygen/ozone treatment, extreme Vitamin C IV drips, and many more) that may or may of not cured anyone of cancer/AIDS (although there is evidence) but has been banned from most major countries
It's a bad idea to sanction treatment that has no actual, research-backed proof of safety and effectiveness. These things are banned to prevent uninformed people from trying to take their health recklessly into their own hands because of how simple and accessible the treatment would be, potentially leading to a lot of deaths if it turns out to be harmful or a ton of people end up doing it wrong. It's an ass-covering safeguard.

Quote:
Originally Posted by zorrobyte View Post
Before everyone gets angry, take some things into consideration. Aluminium is found in peoples brains that have amnesia yet 99% of antiperspirants contain Aluminium as a main ingredient
Sodium is a metal that's highly reactive with water, forming a lot of heat and flammable hydrogen when it reacts, usually ending with an explosion proportionate to the amount of sodium involved. Guess what? The human body is made of ~70% water! AND Sodium is in 100% of table salt! Crazy, isn't it?

Deodorant isn't going to give us all amnesia in the same way you don't die while eating a bag of chips.

Quote:
Originally Posted by zorrobyte View Post
The pesticides used on a majority of our crops is a modified version of Agent Orange which is killing a majority of our servicemen who served in Vietnam while causing widespread birth defects.
Heroin is an opioid that does some nasty things to your circulatory system after prolonged use, but Hydrocodone and Oxycodone are derived from heroin and heroin-like opioids, and have a fine place as medical analgesics.


Quote:
Originally Posted by r31ncarnat3d View Post
No, no, no!

I worked in a research lab in SF focusing on this. It works, it's better than every other chemical treatment we have out there, but it is both far from being a viable cure.

First, let's bring up the issue of legalizing pot: This is absolutely no reason to do so. The concentrations required to retard cancerous cell growth is much too high to get by traditional methods of ingestion. To get the levels required, the compound would have to be purified, concentrated, and injected directly into the target site. Such pharmaceutical grade drugs do not need pot legalized, just as how we have Vicodin yet cocaine is still illegal.

Second, the tests done so far were on rat brains. It's promising, extremely so, but we still need to perform human trials first. Keep in mind that while similar, human brains are not rat brains.
Finally, logic.

The marijuana counterculture will say anything to get their favorite herb legalized. They may or may not have a point in making it easier for researchers to analyze and learn more about pot as treatment/cure.

Quote:
Originally Posted by Kevlo View Post
Thats low.....
It's true, though. You could practically boil down all our actions to being done because of our need for happiness.

Quote:
Originally Posted by taystew View Post
waitwaitwait. folding has actually cured people? i cant find any evidence of this.
For the love of god. That's like saying manufacturing bullets hasn't done anything to contribute to wars .

It's what's done with the results that matter, people. Trigonometry doesn't build bridges; it's the people using it that do.

As for the OP, who clearly just started this thread to get attention, Folding@Home is more constructive for society than letting your computer idle until you feel like shooting something or jacking off.
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post #99 of 133
Quote:
Originally Posted by DEC_42 View Post
As for the OP, who clearly just started this thread to get attention, Folding@Home is more constructive for society than letting your computer idle until you feel like shooting something or jacking off.
Touche...
post #100 of 133
Quote:
Originally Posted by DEC_42 View Post
Sodium is a metal that's highly reactive with water, forming a lot of heat and flammable hydrogen when it reacts, usually ending with an explosion proportionate to the amount of sodium involved. Guess what? The human body is made of ~70% water! AND Sodium is in 100% of table salt! Crazy, isn't it?
This 100%. Chemicals change properties with something as simple as a charge change. Aluminium in compounds is different than aluminium as an ion (Al 3+) which are all different from aluminium metal (Al).

Going off of your example, it's also why peroxide (O2 2-), oxygen molecules (O2), oxygen ions (O 2-), and ozone (O3) all behave differently. Out of those four, there's only one I'd ever inhale on purpose.
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