Yeah I uninstalled the AMD Sata drivers a long time ago and am using the default Microsoft ones you have pictured.
I have only the Nvidia driver installed, no Physx, no audio. I have every audio component disabled all together. HPET off, everything in MSI mode, C states off, Performance mode for both CPU/GPU, you name it.
I just swapped to a GTX 1060 that I borrowed and the issue is still there so definitely not my 2080 Ti. This means the only component that I have not swapped are the SSD and CPU.
Gonna swap SSD on Monday and pray.