Not by default. The bios could be modded for that, but honestly I never hear the fan anyway. Maybe if I had a pcie 4.0 drive that made the chipset work harder but even then you'd have to be using the bottom m2 slot (the top one uses cpu not chipset lanes).
Since I have free time due to the quarantine maybe I'll try to create a generic modded Bios. I was hoping Asus would release a new one since some of their other boards got updates recently but who knows if/when that will happen.