I am also looking at if I should change the the direction of the fans of the system.
Here is a pic of my current system. I will be cooling the VRMs as well.
Pump Res>Lower Rad>Side Rad>VRM Block>Top Rad>CPU>GPU>Pump Res
Currently, I have air being taken in from the bottom of the case, it is exhausted through the top and the side radiator. I have noticed that my case operates at a slight negative pressure with more air being exhausted by the fans than being brought in.
Should I change my top fans to intake air? My temps are good and never go over 50 degrees on the CPU or GPU for gaming.