It all depends on your usage objective.
If you are using this for 24/7 and or gaming, then absolutely no need for more overclocks, the margin of gain is incredibly small and not worth it. However, if you are pushing benchmarks for hwbot scores, or something of that nature, then I would say yes, push it.
Having said that, based on the generation of card you have, I would expect more voltage would not help you. This Maxwell generation is all about DIE temperature and not as much about volts. It scales most with temperature, then once temps are subzero it scales with volts again. Some people, myself included, have literally seen more MHz from under voltage (lower vcore than stock)...because the resulting temps are lower.
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