I have noticed over the years that I will palm a mouse surfing the net or playing low stess games. In a stressful situation I switch to claw more. During long gaming sessions my hand would start to ache. I was using the MX 518 and realized the rear end of the mouse was too large. I switched to the CM Xornet and really loved the shape but I noticed a lag that was effecting my performance. Now I use the Logitech Pro with the Logitech charging mat so I never have to worry about charging the mouse. Yes, it was expensive. The light weight, smaller mice are what I found helps my hands even though I am 6ft tall and pretty large hands.