I've often used a pancake compressor (like contractors often use) to clean out my computer and it did work. However, I would recommend limiting the pressure because I have had fan blades break off before. I can't be certain if it was due specifically to using too much pressure or the fans were just old and cheap. The last time I cleaned my computer I just used an old toothbrush, a qtip, and my own breath. Pulling fans and cleaning them manually is the best way to ensure you don't damage anything.