I love mine.
Some current issues:
Sometimes case fans will spin at the minimum set RPMs in the user-defined curve until I open the tool and click apply again. For some reason they default to 60% if 60% is the minimum I have set instead of spinning at 70% based on the temp sensors chosen for example. I'd imagine a BIOS change can rectify this. I've contacted ASUS.
My SATA6G and USB3 sensors run pretty hot, up to 50-55C at times (during gaming). I believe this is due to my GPU. I wonder what a safe operating temp for those chips is? 75C is a pretty standard min for chips like that so that's what I'm assuming.
Everything else is fantastic, and I have no other issues. Great board!