1. Paper towels around every fitting and around the res
2. Use a fitting on a tube length, attach that fitting to the drain port, make sure it's long enough to travel downwards to a large pot, tub etc
3. open the drain port
4. open top port of the res to let pressure start pushing fluid out
5. wait a while, the fluid will come out, but might take a bit due to air introduced. It may seem like it's done, but shake the tower a little and more may come out. Keep this going until you see most of the gpu block empty. Sometimes blowing into the top rad port helps.
6. If you have a gpu in the loop that is mounted horizontally (normal case), you can unscrew one of the top ports that's unused. keep paper towels in hand in case fluid wants to escape. At this point there's no pressure in the loop, so you should be fine. If it seems that the fluid remains idle, this is when I attach another fitting to that gpu port with a tube length attached to it.
7. Close the res top port. The only open ports should be from the drain and your new tube length to your gpu block. Any other open ports will spit the fluid out (bad news).
8. Start to blow into that tube length, or use a datavac blower. Remember to keep your vessel that's collecting the fluid far and low enough that it doesn't spit fluid on your computer or other things. I like using a big sauce pot with a strainer, I feed the tube through a strainer hole to keep it from moving around when pressure comes through.
9. continue doing this until you see enough drained from your card, and your cpu block is drained below the ports.
10. now you can remove tubing from your gpus, plug those ports with stop fittings, unscrew from rad and remove your gpu from the system, remember there may be fluid dripping from the rads if you didn't blow for long enough. Keep paper towels ready.
11. Now you can start draining your cpu and rads. attach that blower tube to the rad or cpu, whatever is the next connection from your gpu inlet. Then repeat
12. this can be different in your case depending on your build, but I think this may help you understand how to do it without much mess.
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