Hi, nice parts.
Will your front panel fit with that current bend? Seems close from my house.
You could make this connection with a combination of fittings, I think. But, this would introduce a hand two nineties right off the pump outlet which is worst case scenario for these. It's doable but will adversely affect flow.
I would propose rotating pump/res 90* clock wise so fittings are facing you. See mine below - same concept.
for radiators, I simply flush mine with hot tap water for ~5 minutes when new. Then assemble everything using an inline filter before my cpu block to catch any debris and flush with ~1 gallon of distilled water. I run the system and drain the water slowly and top off res as I go through the water.
I think this would allow you a good path for flow:
pump/res - GPU/chipset (parallel) - cpu - top rad - bottom rad - pump res in
I think the chipset really likes parallel flow setup for temperatures. Serial flow resulted in higher temperatures for me.
This also lets you keep the iconic heatkiller cap which makes filling/bleeding MUCH easier, and removes the flow tube from visual.