I'd say that it should be the same, I'd think. But when I first set it up to fold on all 4, I made a mistake and it was folding on two. I think ppd was just a tad over 4k. When I switched to all 4 the ppd was like 8.2k. It might just be coincidence, but if anything, 1 vm should use less resources and less memory and 2.