An example for reference sake:
Up until this week I've been running my system with 2x16GB budget oriented RAM that I slightly overclocked.
From the store it was labeled
DDR4 3200 22:22:22:52 2T
I overclocked it to:
DDR4 3500 17:21:21:42 1T
And I didn't configure any of the secondary or tertiary timings. Reason being I didn't know how to and didn't feel like the work of learning would pay off because it didn't seem like the RAM could be pushed any further. Anyway, it helped the 9600K performance, I noticed the speed increase using it.
I believe my RAM at 3200 gave:
Read speed of 41,838 MB/s
Write speed of 47,593 MB/s
Copy speed of 41,118 MB/s
And a latency slightly more than 60ns
Up at 3500 with somewhat reduced timings (17:21:21:42 vs 22:22:22:52), the RAM's
Read speed was 45,761 MB/s
Write speed was 52,055 MB/s
Copy speed was 44,973 MB/s
And latency was about 55.1ns
Resulting in a
9.4% increased Read performance
9.6% increased Write performance
9.4% increased Copy performance
And a 10.7% lower latency.
Compare those numbers to the ones below which show the increase from disabling Core Isolation/Memory Integrity!
Read speed increases 11.5%
Write speed increases 11.6%
Copy speed increases 15.0%
Latency is reduced by 15.2%
SO!
Disabling Core Isolation/Memory Integrity is like overclocking your RAM by 400 (eg. DDR4 3400 -> 3800), setting your primary timings 3-5 lower, and optimizing your secondary/tertiary timings to 75% of their limit.
Pretty easy and significant performance boost!