That could mean a few things, either you have something like Daemon Tools or another optical drive emulator active, or Securom didn't install properly.
Forgot to mention, it worked fine at first. Then i D/L and installed the patch now I'm getting this error. I do have Daemon Tools installed but its not running.
I wouldn't recommend using CCleaner's registry cleaner, as much as I like CCleaner, registry cleaners cause nothing but trouble (and I've experienced it with CCleaner's time and time again).
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