Well, it really comes down to what you think your data and time is worth, right?
4x drives in RAID-0 would give you pretty darn good performance. Of course, if one drive fails, as you know the entire array goes *poof* and you have to rebuild from scratch. No big deal if you have daily images of the array and it's just a matter of restoring from backup. Bigger deal if you have to reinstall everything from scratch.
Personally, as an opinion, I've avoided RAID-5 arrays like the plague because the write-speeds to them is horrendous, even with hardware RAID controllers with XOR support. For a main workstation, I'd honestly go with a 2-drive RAID-0, and a 2-drive RAID-1. The amount of space is the same as a RAID-5, but I wouldn't be suffering on the write speeds as badly.
If you *must* choose between the two, I'd go with the RAID-0 and get a fifth drive for data backup
.
If you'd be getting a PERC6/i anyways, RAID-10!!!
I'd support you on RAID-10!
P.S. let's not get into any "flame wars" or anything here. The OP is asking for highly subjective *opinions*.

4x drives in RAID-0 would give you pretty darn good performance. Of course, if one drive fails, as you know the entire array goes *poof* and you have to rebuild from scratch. No big deal if you have daily images of the array and it's just a matter of restoring from backup. Bigger deal if you have to reinstall everything from scratch.
Personally, as an opinion, I've avoided RAID-5 arrays like the plague because the write-speeds to them is horrendous, even with hardware RAID controllers with XOR support. For a main workstation, I'd honestly go with a 2-drive RAID-0, and a 2-drive RAID-1. The amount of space is the same as a RAID-5, but I wouldn't be suffering on the write speeds as badly.
If you *must* choose between the two, I'd go with the RAID-0 and get a fifth drive for data backup

If you'd be getting a PERC6/i anyways, RAID-10!!!

P.S. let's not get into any "flame wars" or anything here. The OP is asking for highly subjective *opinions*.